Calcium Orotate+cholecalciferol
About
Calcium Orotate+cholecalciferol belongs to the class of 'dietary supplements primarily used to treat low blood calcium levels. Calcium Orotate+cholecalciferol effectively treats various conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and latent tetany (a muscle disease with low blood calcium levels). Calcium Orotate+cholecalciferol can also be given to pregnant, nursing, and postmenopausal women to ensure that they are getting enough calcium. Additionally, Calcium Orotate+cholecalciferol is used to treat hyperparathyroidism (overactive parathyroid glands) and metabolic bone disease in people with chronic kidney disease, surgery, or other conditions.
Calcium Orotate+cholecalciferol consists of two medicines: Calcium orotate (mineral) and Cholecalciferol (Vitamin D3). Calcium is a mineral that is used to prevent or treat a calcium deficiency. It provides essential nutrients to maintain bone formation and maintenance. Cholecalciferol, also known as Vitamin D3, treats calcium deficiency with hypoparathyroidism (the parathyroid gland's decreased activity) and metabolic bone diseases in people with chronic kidney failure. It raises Vitamin D levels and thereby increases calcium levels in the blood. This helps in improving the absorption rate of calcium from the intestine.
Calcium Orotate+cholecalciferol should be taken in the dose and duration as advised by your doctor. Depending on your medical condition, you are advised to take Calcium Orotate+cholecalciferol for as long as your doctor has prescribed it for you. In some cases, Calcium Orotate+cholecalciferol can cause side effects like constipation or stomach upset, nausea, vomiting, loss of appetite, mood changes, weakness, tiredness, fast or pounding heartbeat, bone/muscle pain, and headache. Most of these side effects of Calcium Orotate+cholecalciferol do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.
If you are known to be allergic to Calcium Orotate+cholecalciferol or its inactive components, please inform your doctor. Pregnant or breastfeeding women should consult their doctor before taking Calcium Orotate+cholecalciferol. Higher doses of Vitamin D than the recommended daily dose should be used in pregnant women only when advised by the doctor. Calcium Orotate+cholecalciferol may pass into the breast milk; hence breastfeeding mothers need to seek medical advice before starting Calcium Orotate+cholecalciferol. Please tell your doctor if you have hypercalcemia (high calcium levels), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food). Brief your medical history if you have any heart/kidney/liver/blood vessel diseases, kidney stones, sarcoidosis (growth of inflammatory cells in different parts of the body), Crohn's disease (inflammatory bowel disease), Whipple's disease (bacterial infection affecting joints and digestive system), achlorhydria (little or no stomach acid), low levels of bile, and phosphate imbalance.
Uses of Calcium Orotate+cholecalciferol
Medicinal Benefits
Calcium Orotate+cholecalciferol is a combination of two drugs, namely; Calcium orotate (mineral), Cholecalciferol (Vitamin D3), used to treat low blood calcium levels and various associated conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and tetany (a muscle disease with low blood calcium levels). Calcium orotate is a mineral that prevents or treats calcium deficiency. It helps to maintain bone and teeth health. It is the only type of calcium penetrating the cell membrane and delivering maximum health benefits to cellular processes. Cholecalciferol, also known as Vitamin D3, treats calcium deficiency with hypoparathyroidism (the parathyroid gland's decreased activity) and metabolic bone diseases in people with chronic kidney failure.
Directions for Use
Storage
Side Effects of Calcium Orotate+cholecalciferol
- Constipation
- Stomach upset
- Nausea/vomiting
- Loss of appetite
- Excessive thirst
- Mood changes
- Bone/muscle pain
- Fast or pounding heartbeat
- Headache
In-Depth Precautions and Warning
Drug Warnings
If you are known to be allergic to Calcium Orotate+cholecalciferol or any other medicines, please tell your doctor. Calcium Orotate+cholecalciferol is not recommended if you have hypercalcemia (high calcium levels), metastatic calcification (extra deposits of calcium in the body), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food). Inform your doctor before taking Calcium Orotate+cholecalciferol if you have any heart/kidney/liver/blood vessel diseases, kidney stones, sarcoidosis (growth of inflammatory cells in different parts of the body), Crohn's disease (inflammatory bowel disease), Whipple's disease (bacterial infection affecting joints and digestive system), achlorhydria (little or no stomach acid), low levels of bile, and phosphate imbalance. If you are pregnant or planning to become pregnant, it is advised to inform your doctor before using Calcium Orotate+cholecalciferol. Higher doses of Vitamin D than the recommended daily dose should be used in pregnant women only when advised by the doctor. Cholecalciferol (vitamin D3) in higher doses may harm the fetus. Calcium Orotate+cholecalciferol may pass into the breast milk; hence consult your doctor before taking Calcium Orotate+cholecalciferol if you are a breastfeeding mother. Calcium Orotate+cholecalciferol should be used with caution in children and only if prescribed by a doctor. Cholecalciferol in Calcium Orotate+cholecalciferol can affect growth in children. Inform your doctor if your child is not growing normally while using the Calcium Orotate+cholecalciferol. Calcium Orotate+cholecalciferol contains aspartame (phenylalanine); hence caution should be taken to have an intolerance to sugars, diabetes, and phenylketonuria (increased levels of an amino acid called phenylalanine).
Drug Interactions
Drug-Drug Interactions: Calcium Orotate+cholecalciferol may interact with calcium supplements (ergocalciferol, cholecalciferol), drugs treating bone loss (alendronate), anticonvulsants (carbamazepine, phenobarbital, phenytoin, primidone), diuretics (bendroflumethiazide, chlortalidone, indapamide), a drug used to treat heart disease (digoxin), medicines to treat tuberculosis (rifampicin, isoniazid), antacids (magnesium hydroxide), steroid medicines (hydrocortisone, prednisolone, dexamethasone), central nervous system stimulants (dextroamphetamine, amphetamine), anti-depressants (duloxetine), anti-ulcer drugs (ranitidine), painkillers (aspirin), anti-clotting drugs (anisindione, dicumarol, warfarin), drugs treating high cholesterol levels (cholestyramine, colesevelam, colestipol), and drugs that treat high blood phosphorus levels (sevelamer), antibiotics (tetracycline, doxycycline, minocycline), quinolone antibiotics (ciprofloxacin, levofloxacin), weight-loss drugs (orlistat).
Drug-Food Interactions: Avoid or reduce the intake of caffeine, soft drinks, and alcohol that inhibit calcium absorption.
Drug-Disease Interactions: Calcium Orotate+cholecalciferol is contraindicated in hypercalcemia (high calcium level in blood), hypervitaminosis D (high vitamin D level in the body), Vitamin D toxicity, malabsorption syndrome, heart/kidney/liver/blood vessel diseases, kidney stones, sarcoidosis (growth of tiny collections of inflammatory cells (granulomas) in any part of your body), Crohn's disease, Whipple's disease (a bacterial infection that most often affects joints and digestive system), achlorhydria (absence of stomach acid), low levels of bile, and phosphate imbalance.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionDrinking alcohol can affect calcium absorption; hence it is advised to limit the alcohol intake while using Calcium Orotate+cholecalciferol.
Pregnancy
cautionCalcium Orotate+cholecalciferol should not be used when pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Calcium Orotate+cholecalciferol.
Breast Feeding
cautionCalcium Orotate+cholecalciferol should not be used in nursing mothers unless clearly necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Calcium Orotate+cholecalciferol.
Driving
cautionCalcium Orotate+cholecalciferol does not impact your ability to drive or operate machinery.
Liver
cautionLet your doctor know if you have any history of liver diseases before taking Calcium Orotate+cholecalciferol. Hepatic impairment/liver disease can alter the metabolic and therapeutic activity of certain Vitamin D forms.
Kidney
cautionIt is advised to seek a doctor's advice before starting Calcium Orotate+cholecalciferol if you have kidney diseases like kidney stones or undergoing dialysis. Calcitriol in Calcium Orotate+cholecalciferol increases inorganic phosphate levels in serum; hence caution should be taken in patients undergoing dialysis to maintain adequate phosphorus levels and avoid ectopic calcification (calcium deposition).
Children
safe if prescribedThe doctor will prescribe the dosage of Calcium Orotate+cholecalciferol based on the child's age and weight.
Habit Forming
Diet & Lifestyle Advise
- Include dairy products like milk, yoghurt, cheese, or milk-based custard in your diet.
- Eat a serving of broccoli, cabbage, bok choy, spinach, and other green leafy vegetables daily.
- Snack on calcium-rich nuts like Brazil nuts or almonds.
- Sprinkle sesame seeds over your food, vegetables, and salads. Sesame seeds are high in calcium.
- Avoid or reduce the intake of caffeine, soft drinks, and alcohol that inhibit calcium absorption.
- Replace the meat with tofu or tempeh for extra calcium in your food.
Special Advise
- Low phosphate diet is recommended to control serum phosphorus levels in patients undergoing dialysis.
- Clinical monitoring of serum electrolyte concentrations and cardiac function is recommended.
Patients Concern
Disease/Condition Glossary
Osteoporosis: Osteoporosis is a bone disease that weakens and brittle bones by decreasing bone density. As bones become less dense, they weaken and are more likely to break. Breaking a bone is a serious complication of osteoporosis, especially in older patients. Women are much more likely to develop osteoporosis than men. Signs and symptoms include back pain caused by a fractured or collapsed vertebra, loss of height over time, a stooped posture, and a bone that breaks much more easily than expected.
Osteomalacia/Rickets: A bone disease caused by softening and weakening bones in children due to inadequate vitamin D. Adults can experience a similar condition known as osteomalacia. It causes bone pain, poor growth, and soft, weak bones that can lead to bone deformities.
Tetany: A disease condition due to low levels of calcium (hypocalcemia) in the body that causes cramps and spasms in the hands, feet, and larynx (voice box).
Hypoparathyroidism: It is a disease characterized by low levels of parathyroid hormone. This can cause low calcium levels and trigger tetany.
FAQs
Calcium Orotate+cholecalciferol is a combination of two medicines: Calcium orotate (mineral) and Cholecalciferol (Vitamin D3). Cholecalciferol helps your body absorb Calcium Carbonate and supports the muscles needed to avoid falls. Calcium helps build and maintain bones. Collectively, Calcium Orotate+cholecalciferol used to treat osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and tetany (a muscle disease with low blood calcium levels).
Calcium Orotate+cholecalciferol can cause kidney stones due to excess calcium deposition when used for a prolonged period. Please consult your doctor before taking Calcium Orotate+cholecalciferol as a daily supplement if you have kidney problems or kidney stones history.
If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose, and follow your usual dosage.
Cholecalciferol in Calcium Orotate+cholecalciferol can increase inorganic phosphate levels in serum; hence it should be cautiously used in patients undergoing dialysis to maintain adequate phosphorus levels and avoid ectopic calcification (calcium deposition). It is advised to follow a low phosphate diet to control serum phosphorus levels in dialysis patients.
Calcium Orotate+cholecalciferol is used to increase low levels of calcium in the body. Hence it is not advised to use Calcium Orotate+cholecalciferol during hypercalcemia since it causes an overdose of calcium leading to kidney stones and other effects.
